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CGNOC are committed to providing reliable evidence required to make important decisions on issues concerning Gynaecological cancers, Neuro-oncology and related topics.
CGNOC's main task is to facilitate the identification of reports of controlled clinical trials and to carry out systematic reviews which are then published on the Cochrane Library. The reviews are updated as new evidence is identified. This ensures that Cochrane reviews are relevant, useful, usable and used.
Evidence relating to the care of people with cancer comes from a number of sources and so a multi-faceted approach is taken, including searching electronic databases of clinical trial reports, handsearching printed journals, and scanning of the 'grey' literature i.e. conference proceedings and abstracts. Every effort is made to find unpublished trials to avoid bias.
The Group's Co-ordinating Editor for gynaecological oncology is Jo Morrison, whose responsibilities are to ensure that each stage of the process (the title, the protocol, the review and subsequent updates) meet the rigorous Methodological Expectations for Cochrane Intervention Reviews (MECIR) standards and are reviewed by a variety of specialists including consumer advocates. Jo is a Consultant Gynaecological Oncologist at the Somerset Gynaecological Cancer Centre in Taunton, with a special interest in colposcopy and gynaecology enhanced recovery programmes. Jo also represents the South West of England on the board of the British Gynaecological Cancer Society.
The remit of the gynaecological oncology aspect of CGNOC is to conduct systematic reviews in the following cancer sites and topic areas:
• Uterine cervix
• Body of uterus
• Vagina/fallopian tube
• Screening for pre-malignant changes
• Strategies for early detection of cancer
• Treatment of early disease
• Treatment of late disease
The Cochrane Gynaecological, Neuro-oncology & Orphan Cancer Group also provide Cochrane with an editorial base for cancer reviews outside the scope of any current Cochrane Group (CG). Topic areas include;
• Soft tissue sarcomas
• Aspects of care of cancer patients not relating to cancer of a specific site e.g. infections in people with cancer.
• Palliative and supportive care (in conjunction with the Pain, Palliative and Supportive Care Group)
• Psychosocial interventions and outcomes, including rehabilitation
Development of the neuro-oncology list within the CGNOC has been necessitated by the improving quality of research in evidence based neuro-oncology and plethora of new reviews. The group aims to provide a focal point within Cochrane to facilitate a coherent network to locate reviews. The reviews in this area are managed by Co-ordinating Editors Robin Grant and Mike Hart. Robin is a Consultant Neurologist at the Edinburgh Centre for neuro-oncology (ECNO) which is based within the Western General Hospital, Edinburgh, UK. ECNO provides a base for administrative and clinical integration of staff from Neurology, Neurosurgery and Oncology who have a special interest in neuro-oncology and who are involved in the joint neuro-oncology clinic. Robin is the Past President of the European Association of neuro-oncology. Mike Hart is a Specialty Trainee in neuro-oncology at Addenbrooke's Hospital, Cambridge, UK.
The CGNOC links with other CGs to share ideas. It also works with fields and methods working groups to ensure that its reviews are of the highest quality. CGNOG often has common areas of interest with other Cochrane Groups, notably Pain, Palliative and Supportive Care Group, Menstrual Disorders and Subfertility Group and all other Cochrane Groups with cancer in their scope. Every effort is made to avoid duplication.
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